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exocell.jpgexocell.jpg

艾美捷科技代理Exocell品牌。

Exocell公司是一家专注于糖尿病及其并发症研究相关的产品与服务的生物制品公司。Exocell公司由Margo Cohen于1988年创立,致力于开发与糖尿病及其并发症相关的诊断产品。随着公司的不断发展,Exocell迅速成为该领域的重要供应商,拥有15项专利和2000多项研究引用。目前,Exocell产品已成为Ethos Biosciences(Ott Scientific的一部分)的一部分,继续为全球的学术、生物技术和制药研究团队提供服务。


Exocell产品与服务包括:

(1)临床诊断产品:

Albuwell:用于检测微白蛋白尿,是早期糖尿病性肾功能紊乱的明确标志物。

Creatinine:用于检测尿中的肌酐。

Glycaben:用于监测糖化白蛋白(中期的控糖指标)。

Glycacor:用于检测糖化LDL(短期控糖指标及心血管疾病风险指标)。

Hemoglobin A1c参照标准:长期控糖指标。


(2)临床研发类检测试剂与试剂盒:

Apo B Test:用于检测人血浆中的apolipoprotein B。

Collagen IV H:用于检测样本中的IV型胶原。

hFibronectin ELISA试剂盒:用于检测人血浆中的fibronectin。

Nephrin ELISA试剂盒:用于检测尿液中的nephrin等。


(3)实验室研究相关产品:

Albuwell M:用于检测小鼠样本中的微白蛋白尿。

Nephrat II:用于检测大鼠样本中的微白蛋白尿。

Glyco-Albumin R:用于检测大鼠血清中的糖化白蛋白等。


(4)糖尿病及其并发症研究相关的试剂及标准参照品:

A717:抗糖化白蛋白单克隆抗体。

E85:抗糖化血红素的单克隆抗体。

ES12:抗糖化LDL的单克隆抗体等。



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Chiralix.jpg

艾美捷科技特约代理Chiralix公司产品。

Chiralix是一家专业从事手性有机分子合成和供应的公司,致力于制药公司及生命科学研究领域的实验室研究用特有手性分子的生产和研发。Chiralix集先进的有机分子合成、过渡金属催化、生物催化技术于一身,具备灵活与高效的多种手性分子合成工艺,如基团的氨基酸,叠氮酸,氨基醇及多种肽段模块。除了提供大量的手性分子成品,还提供优质的研发服务,如复杂有机分子的合成等。

 

Chiralix is a specialist in chiral organic synthesis. We offer a unique range of chiral drug-like building blocks on research-scale, aimed at research laboratories in pharmaceutical companies and all others involved in the Life Sciences industry. The integration of our capabilities in the areas of advanced organic synthesis, transition metal catalysis and biocatalysis, enables us to develop flexible and efficient synthetic routes to diversely substituted chiral molecules, such as specialty amino acids, azido acids, amino alcohols and peptide building blocks. In addition to our catalog of unique building blocks, we provide high quality contract research services for our clients in support of their own research efforts. Our services include the custom synthesis of complex organic molecules and the parallel synthesis of compound libraries.

 

Chiralix公司的主要服务包括:

Custom synthesis

Parallel synthesis of focused client-directed compound libraries

Route scouting

Disease state human plasma


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2.5比1.pngexocell.jpg

艾美捷科技代理Sequins品牌。

sequins.bio 是一家解决基因组学领域核心痛点——数据质量、可靠性和标准化——的创新公司。他们开发的合成 DNA 标准品 “sequins” 作为一种“分子尺子”和“内部间谍”,被整合到样本中一起进行测序分析,为整个流程提供了前所未有的透明度和可溯源性。这使得实验室能够:监控实验过程偏差;评估技术和流程性能;验证生物信息分析结果的准确性;标准化不同来源的数据。

         IMG_20250626_142550.jpg   IMG_20250626_141842(1).png       IMG_20250626_142621.jpg       

尤其在精准医疗和临床诊断领域,sequins.bio 的技术对于确保基因检测结果的可靠性和可比性,从而支持准确的临床决策至关重要。他们代表了基因组学质量控制从简单的“输入/输出”检查向基于已知真相的、全流程、分析性能导向的质控演进的重要方向。


核心业务包括:

● 全基因组测序(WGS):已成为识别致病性遗传变异的有力工具。

● 宏基因组学(Metagenomics):能够实现对病原体检测和抗微生物药物耐药性筛查的精准微生物分析。

● 循环肿瘤DNA(ctDNA)检测:Sequins内标标准品为ctDNA检测提供了有力的质控工具。



更多详情请咨询→

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全国免费热线:400-6800-868

直拨专线:+86-027-59626688;18771997407

客服QQ一:17754422825;

客服QQ二:18771149750

公司地址:武汉市洪山区光谷大道35号光谷总部国际时代 二期1栋13

咨询和订购邮箱:sales@amyjet.com 


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Chiralix.jpg

艾美捷科技特约代理Chiralix公司产品。

Chiralix是一家专业从事手性有机分子合成和供应的公司,致力于制药公司及生命科学研究领域的实验室研究用特有手性分子的生产和研发。Chiralix集先进的有机分子合成、过渡金属催化、生物催化技术于一身,具备灵活与高效的多种手性分子合成工艺,如基团的氨基酸,叠氮酸,氨基醇及多种肽段模块。除了提供大量的手性分子成品,还提供优质的研发服务,如复杂有机分子的合成等。

 

Chiralix is a specialist in chiral organic synthesis. We offer a unique range of chiral drug-like building blocks on research-scale, aimed at research laboratories in pharmaceutical companies and all others involved in the Life Sciences industry. The integration of our capabilities in the areas of advanced organic synthesis, transition metal catalysis and biocatalysis, enables us to develop flexible and efficient synthetic routes to diversely substituted chiral molecules, such as specialty amino acids, azido acids, amino alcohols and peptide building blocks. In addition to our catalog of unique building blocks, we provide high quality contract research services for our clients in support of their own research efforts. Our services include the custom synthesis of complex organic molecules and the parallel synthesis of compound libraries.

 

Chiralix公司的主要服务包括:

Custom synthesis

Parallel synthesis of focused client-directed compound libraries

Route scouting

Disease state human plasma


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Milenia Biotec.jpg

Milenia Biotec为全世界生物医药、诊断企业和研究机构提供高品质的免疫诊断试剂盒。

 

Milenia Biotec offers immunodiagnostic kits, that are distributed worldwide from our headquarters in Giessen. Our test systems help to carefully and rapidly diagnose various diseases. The results are the basis for medical doctors to do a targeted therapeutic approach. Therefore unneccessary therapies or hospital admissions can be saved and patients can be more comfortable.

 

Our tests are very simple to run and they can be done at every location. For the calculation of results only minimal equipment is required. For instance, the "PolyCheck" products are read on a standard flat bed scanner. The lateral flow technology, on which our "QuickLine" Assays are based, even allows testing without any instrumentation!

 

Milenia Biotec公司的产品主要有:

产品名称

产品编号

产品描述

Acanthocheilonema   viteae (OWN) - IgG Antibodies

AF   9400

Item   number: AF 9400
  Package size: 96 Tests
  Test procedure: 15 min RT + 1,5 h 37° C
  Standard range: quality based on cut-off  test
  Range: pNPP, λ=405   nm
  Sample volume:10 μl   serum for pre-dilution

HAMA

MQHM   Z

Item   number: MQHM Z
  Package size: 5 Tests
  Test procedure: 10 min RT
  Evaluation: quality based on evaluation card
  Sample volume: 50 μl   serum
  Specificity: IgG antibodies against mouse IgG

HIT

MQHIT Z; MQHIT 1

  Item number; MQHIT Z; MQHIT 1
  Package size: 5 Tests; 20 Tests
  Test procedure: 10 min RT
  Evaluation quality based on evaluation card
  Range: n.a.
  Detection limit: n.a.
  Sample volume: 5 μl serum
  Specificity IgG antibodies against PF4 / polyanion-complexes

HIT   Positive Control

MQCOHIT 1

Item   Number: MQCOHIT 1
  Package size: 1 x 1 Fl. à 0,25 ml
  for analyte: IgG antibodies against PF4 / polyanion complexes
  Concentration: positive
  Evaluation: visually

IL-6

MQL6 1

Item   number: MQL6 1
  Package size: 20 Tests
  Test procedure: 20 min RT
  Range: ≤ 50 bis ≥ 10.000 pg/ml
  Detection limit: 50 pg/ml
  Sample volume: 100 μl serum, plasma, liquor or culture supernatant

IL-6   Control

MQCO6 1

Item   Number: MQCO6 1
  Package size: 2 x 3 Fl.
  for analyte: IL6
  Concentration: Two areas
  Evaluation: only Milenia® POCScan Reader

Aspergillus   fumigatus - IgG Antibodies

AF 6100

Item   number: AF 6100
  Package size: 96 Tests
  Test procedure: 15 min RT + 1,5 h 37° C
  Standard range: quality based on cut-off test
  Range: pNPP, λ=405 nm
  Sample volume: 10 μl serum for pre-dilution

Echinococcus   multilocularis Em2 - Em18 Antibodies IgG

AF 9300

Item   number: AF 9300
  Package size: 96 Tests
  Test procedure: 15 min RT + 1,5 h 37° C
  Standard range: quality based on cut-off test
  Range: pNPP, λ=405 nm
  Sample volume: 10 μl serum for pre-dilution

Echinococcus   multilocularis Em18 Antibodies IgG

AF 9310

Item   number: AF 9310
  Package size: 96 Tests
  Test procedure: 15 min RT + 1,5 h 37° C
  Standard range: quality based on cut-off test
  Range: pNPP, λ=405 nm
  Sample volume: 10 μl serum for pre-dilution

Echinococcus   granulosus (dog tapeworm) - IgG Antibodies

AF   9350

Item   number: AF 9350
  Package size: 96 Tests
  Test procedure: 15 min RT + 1,5 h 37° C
  Standard range: quality based on cut-off test
  Range: pNPP, λ=405 nm
  Sample volume: 10 μl serum for pre-dilution

Leishmania   infantum - IgG Antibodies

AF 9500

Item   number: AF 9500
  Package size: 96 Tests
  Test procedure: 15 min RT + 1,5 h 37° C
  Standard range: quality based on cut-off test
  Range: pNPP, λ=405 nm
  Sample volume: 10 μl serum for pre-dilution

Entamoeba   histolytica - IgG Antibodies

AF 9550

Item   number: AF 9550
  Package size: 96 Tests
  Test procedure: 15 min RT + 1,5 h 37° C
  Standard range: quality based on cut-off test
  Range: pNPP, λ=405 nm
  Sample volume: 10 μl serum for pre-dilution

Microsporidia

 AF 8100

Item   number: AF 8100
  Package size: 2 x 50 Tests
  Test procedure: 10 min (-)20° C + 70 min RT
  Sample volume: 2 μl stool suspension

Schistosoma   mansoni IgG

AF 9600

Item   number: AF 9600
  Package size: 96 Tests
  Test procedure: 15 min RT + 1,5 h 37° C
  Standard range: quality based on cut-off test
  Range: pNPP, λ=405 nm
  Sample volume: 10 μl serum for pre-dilution

Enzyme   immunoassay in microplate format with 12 x 8 strips

AF 9450

Item   number: AF 9450
  Package size: 96 Tests
  Test procedure: 15 min RT + 1,5 h 37° C
  Standard range: quality based on cut-off test
  Range: pNPP, λ=405 nm
  Sample volume: 10 μl serum for pre-dilution

Toxocara   canis (roundworm) - IgG Antibodies

AF 9200

Item   number: AF 9200
  Package size: 96 Tests
  Test procedure: 15 min RT + 1,5 h 37° C
  Standard range: quality based on cut-off test
  Range
  Sample volume: 10 μl serum for pre-dilution

Milenia®   GenLine Universal modul

MGUP 1

Item   number: MGUP 1
  Package size: 48 Tests
  Test procedure: 55 min (50 min Thermocycler + 5 min RT)
  Evaluation: qualitatively
  Standard range: n.a.
  Detection limit: n.a.
  Sample volume: 2 µl
  Specificity: Amplifikate der Milenia GenLine PCR Module

Milenia®   GenLine Lactobacillus/Pediococcus Screen

MGScLP 1

Item   number: MGScLP 1
  Package size: 48 Tests
  Test procedure: 55 min (50 min Thermocycler + 5 min RT)
  Evaluation: qualitatively
  Standard range: n.a.
  Detection limit: 10^4 – 10^5 germs/ml
  Sample volume: 2 µl
  Specificity: Bierschädigende Lactobacillen und Pediococcen

Milenia®   GenLine Megasphaera/Pectinatus Screen

MGScMP 1

Item   number: MGScMP 1
  Package size: 48 Tests
  Test procedure: 55 min (50 min Thermocycler + 5 min RT)
  Evaluation: qualitatively
  Standard range: n.a.
  Detection limit: 10^4 – 10^5 gems/ml
  Sample volume: 2 µl
  Specificity: Bierschädigende Megasphaeren und Pectinaten

Milenia®   GenLine Lactobacillus brevis

MGLBR Z

Item   number: MGLBR Z
  Package size: 24 Tests
  Test procedure: 55 min (50 min Thermocycler + 5 min RT)
  Evaluation: qualitatively
  Standard range: n.a.
  Detection limit: 10^4 – 10^5 germs/ml
  Sample volume: 2 µl
  Specificity: Bierschädigender Lactobacillus brevis

Milenia®   GenLine Hop Resistance Screen Kit

MGHOR 1

Item   number: MGHOR 1
  Package size: 48 Tests
  Test procedure: 55 min (50 min Thermocycler + 5 min RT)
  Evaluation: qualitatively
  Standard range: n.a.
  Detection limit: n.a.
  Sample volume: 2 µl
  Specificity: HOR A and HOR C Gene

HybriDetect

MGHD 1

Item   number: MGHD 1
  Package size: 100 Tests
  Sample volume: 100 μl

HybriDetect   2T

MGHD2 1

Item   number: MGHD2 1
  Package size: 100 Tests
  Sample volume: 100 μl

Milenia®   Mouse Immunoglobulins-universal module

MQUM 1

Item   number: MQUM 1
  Package size: 100 Tests
  Test procedure: 5 min RT
  Evaluation: qualitatively visually
  Standard range: n.a.
  Detection limit: 1 - 20 µg/ml
  Sample volume: 10 µl
  Specificity: Mouse immunoglobulins

Milenia®   Mouse IgG1

MQSBG1

Item   number: MQSBG1
  Package size: 10 Tests
  Test procedure: 5 min RT
  Evaluation: qualitatively visually
  Standard range: n.a.
  Detection limit: 1 - 20 µg/ml
  Sample volume: 10 µl
  Specificity: Mouse IgG1

Milenia®   Mouse IgG2a

MQSBG2A

Item   number: MQSBG2A
  Package size: 10 Tests
  Test procedure: 5 min RT
  Evaluation: qualitatively visually
  Standard range: n.a.
  Detection limit: 1 - 20 µg/ml
  Sample volume: 10 µl
  Specificity: Mouse IgG2a

Milenia®   Mouse IgG2b

MQSBG2B

Item   number: MQSBG2B
  Package size: 10 Tests
  Test procedure: 5 min RT
  Evaluation: qualitatively visually
  Standard range: n.a.
  Detection limit: 1 - 20 µg/ml
  Sample volume: 10 µl
  Specificity: Mouse IgG2b

Milenia®   Mouse IgG2c

MQSBG2C

Item   number: MQSBG2C
  Package size: 10 Tests
  Test procedure: 5 min RT
  Evaluation: qualitatively visually
  Standard range: n.a.
  Detection limit: 1 - 20 µg/ml
  Sample volume: 10 µl
  Specificity: Mouse IgG2c

Milenia®   Mouse IgG3

MQSBG3


  Item number: MQSBG3
  Package size: 10 Tests
  Test procedure: 5 min RT
  Evaluation: qualitatively visually
  Standard range: n.a.
  Detection limit: 1 - 20 µg/ml
  Sample volume: 10 µl
  Specificity: Mouse IgG3

Milenia®   Mouse IgM

MQSBM

Item   number: MQSBM
  Package size: 10 Tests
  Test procedure: 5 min RT
  Evaluation: qualitatively visually
  Standard range: n.a.
  Detection limit: 1 - 20 µg/ml
  Sample volume: 10 µl
  Specificity: Mouse IgM

Milenia®   Mouse IgA

MQSBA

Item   number: MQSBA
  Package size: 10 Tests
  Test procedure: 5 min RT
  Evaluation: qualitatively visually
  Standard range: n.a.
  Detection limit: 1 - 20 µg/ml
  Sample volume: 10 µl
  Specificity: Mouse IgA

Milenia®   Mouse kappa

MQSBKLC

Item   number: MQSBKLC
  Package size: 10 Tests
  Test procedure: 5 min RT
  Evaluation: qualitatively visually
  Standard range: n.a.
  Detection limit: 1 - 20 µg/ml
  Sample volume: 10 µl
  Specificity: Mouse kappa

Milenia®   Mouse lambda

MQSBLLC

Item   number: MQSBLLC
  Package size: 10 Tests
  Test procedure: 5 min RT
  Evaluation: qualitatively visually
  Standard range: n.a.
  Detection limit: 1 - 20 µg/ml
  Sample volume: 10 µl
  Specificity: Mouse lambda

Milenia®   GenLine Alicyclobacillus Screen

MGScACB   1

Item   number: MGScACB 1
  Package size: 48 Tests
  Test procedure: 75 min (20 min Sample Processing + 55 min Thermocycler + 5   min RT)
  Evaluation: qualitatively
  Standard range: n.a.
  Detection limit: 10^3 – 10^4 germs/ml
  Sample volume: 2 µl
  Specificity: Beverage-damaging Alicyclobacillen

Milenia®   GenLine Alicyclobacillus acidoterrestris / Guajacol

MGAaG   Z

Item   number: MGAaG Z
  Package size: 24 Tests
  Test procedure: 75 min (20 min Sample Processing + 55 min Thermocycler + 5   min RT)
  Evaluation: qualitatively
  Standard range: n.a.
  Detection limit: 10^3 – 10^4 germs/ml
  Sample volume: 2 µl
  Specificity: Alicyclobacillus acidoterrestris and ability to form guaiacol

Milenia®   GenLine Extraction buffer

MGEXBA

Item   number: MGEXBA
  Package size: 10 ml

Milenia®   GenLine Swab Detection Buffer

MGSDB

Item   number: MGSDB
  Package size: 10 ml



更多详情请联系 

艾美捷科技有限公司

全国服务热线:400-6800-868

邮箱:sales@amyjet.com

网站:www.amyjet.com


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ReVacc 2.5比1.pngexocell.jpg

艾美捷科技代理ReVacc Scientific品牌


ReVacc Scientific为科学发现、临床诊断和疾病治疗提供可靠的病毒学和免疫学产品和服务。


▍ReVacc Scientific公司产品

● 假病毒:带有报告基因(如荧光素酶)的假病毒,为样本高通量筛选提供了高效的解决方案。基于多种技术平台,ReVacc Scientific生产针对冠状病毒、丝状病毒或高致病性禽流感病毒的假病毒。

● 重组蛋白:公司专注于生产带有关键中和表位的蛋白质,这些蛋白质应用在疫苗、诊断和治疗三大重要领域。核心优势有:使用真核表达系统(哺乳/昆虫细胞)确保获得正确的翻译后修饰;生产的蛋白质能正确组装成其天然的多聚体状态(如二聚体、三聚体)。

● 单克隆抗体:大多数抗体具有中和活性,具有阻断病原体感染细胞的能力。

● 检测试剂盒:用于检测人、小鼠或兽医动物样本中的 IgG 或抗原水平,操作简便。

● 克隆工具:一步法高效组装;一分钟高效转化。


ReVaccScientific.png


▍ReVacc Scientific公司服务

● 样本中和抗体效价评估:在符合生物安全要求的前提下,为您测定样本的中和活性;

● 定制化蛋白生产:根据需求生产携带特定突变的定制化蛋白;

● 定制化假病毒构建:根据需求生产携带特定突变的定制化假型病毒。

● 诊断试剂盒定制开发:根据需求开发定制试剂盒

● 定制化抗体发现:开发了多色表位特异性单细胞分选技术 (MESCS®),并结合重组单克隆抗体技术,从不同物种样本中发掘有价值的抗体。

● 抗体工程化改造:抗体人源化、抗体标记、抗体核苷酸序列测定、抗体同种型转换抗体格式转换以及抗体种属转换。

● 流式细胞分选服务:用于分选具有特定光散射和荧光特性的细胞群。


▍ReVacc Scientific部分产品列表

分类品名货号规格
Pseudovirus ReporterVSV-Pseudovirus_SARS-CoV-2 WT (Wuhan Strain) Spike with luciferase reporterP14N41200 μl;1000 μl
Pseudovirus ReporterPseudovirus_RSV Fusion with Luciferase Reporter (A2 strain)P11A48200 μl;1000 μl
Pseudovirus ReporterLenti-Pseudovirus_SARS-CoV-2 (Wuhan Strain) Spike with luciferase reporterO21F291.1ml;5.5ml
Pseudovirus ReporterVSV-Pseudovirus_MERS-CoV Spike with luciferase reporterT53L53200 μl;1000 μl
Pseudovirus ReporterVSV-Pseudovirus_SARS-CoV (2003 strain) Spike with luciferase reporterV44X39200 μl;1000 μl
Monoclonal AntibodyAnti-Dengue E Domain III Monoclonal Neutralizing AntibodyK34Q76100 μg;500 μg
Monoclonal AntibodyAnti-Ebola Broad Neutralizing AntibodyP5N48100 μg;500 μg
Monoclonal AntibodyAnti-HCV E2 Neutralizing Monoclonal AntibodyX81H49100 μg;500 μg
Monoclonal AntibodyAnti-Herpes Simplex Virus gD AntibodyY48B93100 μg;500 μg
Monoclonal AntibodyRecombinant Human Anti-hMPV Fusion IgM AntibodyR7V2720 μg;100 μg
Monoclonal AntibodyRecombinant Human Anti-hMPV Fusion IgA AntibodyA89X220 μg;100 μg
Recombinant ProteinDengue virus 1 E proteinR22F8100 μg;500 μg
Recombinant ProteinEbola Sudan GP proteinB78A28100 μg;500 μg
Recombinant ProteinEbola Zaire Makona GP proteinP54P89100 μg;500 μg
Recombinant ProteinHerpes simplex virus (HSV) gD protein (Type 1)L61Q82100 μg;500 μg
Recombinant ProteinHIV-1 Trimeric GP140 protein-clade B, YU2 strainW44H24100 μg;500 μg
Test kitHuman Kallikrein 3/PSA Quantitative ELISA (Ultra-sensitive)S64N8696-well
Test kitHuman Anti-Cytomegalovirus gB Protein Antibody IgG Titer Serologic Assay KitW19V4296-well
Test kitHuman Anti-Dengue Antibody IgG Titer Serologic Assay Kit (E)P76A6496-well
Test kitHuman Anti-Ebola Antibody IgG Titer Serologic Assay Kit (Trimeric GP)P78G8696-well
Test kitHuman Anti-HIV-1 Antibody IgG Titer Serologic Assay Kit (Trimeric GP140)R29T1896-well
CloningSeamless Assembly Master Mix (2X)Q72R5650μl; 250μl;1ml
CloningOne-Minute Competent Cells (Stbl2 similar)L86Z198 x 50 μl; 96 x 50 ul
CloningOne-Minute Competent Cells (DH5 Alpha)L2A18 x 50 μl; 96 x 50 ul




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Cayman Chemical.jpg

Cayman Chemical向全球科学工作者提供多研究领域的生化、免疫试剂和分析试剂盒,其产品被广泛应用于肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等不同研究领域。Cayman Chemical可提供用于检测的特色试剂盒,如:类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等;也提供多种高质量试剂,包括:类花生酸类物质、氧化氮试剂及许多相关脂质、脂肪酸、酶和抗体。"

 

Cayman Chemical Company is an American biotechnology company founded in 1980, headquartered in Ann Arbor, MI. The company provides chemicals that are used primarily by universities and pharmaceutical companies for research and the development of medicines. The company is also known as a provider of reference standards to state and federal crime labs for use in the detection of rapidly evolving designer drugs. Small quantities of these known reference standards are analyzed using mass spectrometry and gas chromatography techniques to match against forensic evidence, usually confiscated by law enforcement, or forensic toxicological evidence collected in the form of biological samples such as urine, blood, or tissue.

 

Cayman chemical的主要产品包括:

Chemical Analysis

Chemical Synthesis

Bioanalysis

Medicinal Chemistry

Prostaglandin APIs

R&D Services

Manufacturing

Biochemicals

Assay Kits

Antibodies

Proteins

Analytical Standards

Certified Reference Materials

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