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Dendritics公司主要关注人类树突状细胞,希望找到能够促使CD34+造血前体细胞转化为树突状细胞(在GM-CSF和TNF-alpha存在的情况下)的细胞因子。在1992-2005年间,大量的研究使得研究者对人类树突状细胞的产生、细胞通路、C-type凝集素受体的功能及Toll-like受体的活性有了更深的理解。

 

DENDRITICS was started in 2005 by former members of SCHERING PLOUGH Laboratory for Immunological Research (LIR) in Dardilly, France. From their long experience at LIR, the team members of DENDRITICS have gathered complementary scientific and technological knowledge in different areas of immunology. The initial focus of LIR was in the biology of B lymphocytes, elaboration of human monoclonal antibodies, and in cytokine discovery (IL-3, IL-4, IL-7, IL-10, IL-17, GM-CSF) together with our colleagues of DNAX Research Institute in Palo Alto, California.

 

Our interest in cytokines led to the finding that human dendritic cells (DCs) could be generated in vitro from CD34+ hematopoietic progenitors cultured in the presence of GM-CSF and TNF-alpha.

 

The period from 1992 to 2005 saw the specialization of LIR in DC biology and was fuelled by a large-scale effort to discover and study the function of genes specifically expressed by these cells. This program led to a number of findings that contributed in particular to understanding the heterogeneity of DCs, the pathways regulating DC migration, the function of C-type lectin receptors in DCs and the activity of Toll-like receptors in DCs. Many novel genes were discovered through screening of cDNA libraries or through monoclonal antibodies raised against DCs.

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艾美捷科技代理Novocib品牌全系列产品


Novocib是一家成立于2005年的生物技术公司,专注于核苷酸代谢领域。公司开发了一系列用于细胞、食品和饲料原料中核苷酸分析的创新产品与服务,包括:全谱核苷酸分析服务、核苷酸酶检测试剂盒,核苷酸代谢纯化活性酶以及富含核苷酸的新产品和原料开发协助。


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Novocib产品线

● 核苷酸分析:

包含全谱核苷酸分析,其涵盖杂环碱基、核苷、核苷酸以及核酸(DNA 和 RNA);酵母提取物中核苷、5'-核苷酸及核酸分析以及食品或饲料原料中嘌呤,嘧啶分析。


货号品名
#S1200-03Yeast Extract Nucleotides Analysis
#S1200-04Cellular Nucleotides Analysis
#S1200-05Nucleic acid RNA and DNA quantification by HPLC-UV analysis
#S1200-06HPLC-UV analysis for purines

● PRECICE®一步法试剂盒:

预置精确定量的酶、缓冲液、辅因子及底物,浓度均为最佳配比;采用 96 孔微孔板规格;便捷省时,避免潜在操作误差。


品名中文名称货号规格
PRECICE® HPRT Assay Kit次黄嘌呤磷酸核糖基转移酶检测试剂盒#K0709-01-210 ml, 24 analyses (8 samples in triplicate)
PRPP-S Assay Kit磷酸核糖焦磷酸合成酶活性检测试剂盒#K0709-04-210 mL of reaction mixture (half 96-well plate)
Ampda Assay Kit腺苷酸脱氨酶检测试剂盒#K0709-05-112 analyses (5 ml reaction buffer)
Ampda Assay Kit腺苷酸脱氨酶检测试剂盒#K0709-05-224 analyses (10 ml reaction buffer)
Itp Ase Assay Kit肌苷三磷酸焦磷酸酶活性检测试剂盒#K0709-06-210 mL of reaction mixture (half 96-well plate)
Adk Phosphorylation Assay Kit腺苷酸激酶检测试剂盒#K0507-021 plate (96 assays)
Dck Phosphorylation Assay Kit脱氧胞苷激酶检测试剂盒#K0307-011 plate (96 assays)
Adk Assay Kit腺苷酸激酶检测试剂盒#K0507-01.011 plate (96 assays)
Adk Assay Kit腺苷酸激酶检测试剂盒#K0507-01.055 plates (5 x 96 assays)
Phosphatase Assay Kit磷酸酶通用检测试剂盒#K0211-011 plate (96 assays)

● 活性纯化酶制剂:

核苷激酶;嘌呤代谢酶;支持微量至批量订购


品名中文名称货号规格
Human IMPDH, Type II肌酐一磷酸脱氢酶2#E-Nov150 mU;100 mU;250 mU
Human Recombinant Pnp人嘌呤核苷酸磷酸化酶#E-Nov220 Units;40 Units;120 Units
Recombinant Deoxycytidine Kinase脱氧胞苷激酶#E-Nov3500 mUnits;2 Units
Human Ump Cmp Kinase胞质型 UMP-CMP 激酶#E-Nov41 Unit;5 Units
Recombinant Adenosine Kinase人腺苷酸激酶#E-Nov5100 mUnits;200 mUnits;500 mUnits
Human cytosolic 5'-nucleotidase II (cN-II)5'-核苷酸酶 II#E-Nov650 mUnits;150 mUnits
Bacterial Recombinant Impdh肌苷一磷酸脱氢酶#E-Nov750 mUnits
Bacterial FMN-reductase from Escherichia coli (Fre)FMN 还原酶#E-Nov825 Units;50 Units;100 Units
Human Recombinant Hgprt人次黄嘌呤磷酸核糖基转移酶#E-Nov9100 mUnits - 4 tubes with 25 mUnits each
Highly Pure Bacterial Luciferase细菌荧光素酶#E-Nov101 mg;2 mg;5 mg


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LKT Labs是一家专注于特殊化学品研究和开发的公司。主要提供:药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料。

 

LKT Laboratories is a biochemical supply company focused on the synthesis, purification, and isolation of small molecules for research applications. Its range of products exhibit known biological activities that have found uses in a wide array of research fields, especially cancer and neuroscience. These products include protein kinase inhibitors, ion channel modulators, and activators.

 

Originally established in 1989 as a research company doing government grant work with exactly these types of molecules, LKT Labs has a unique understanding of the needs of its customers. Its goal is to provide laboratories around the world with a reliable and diverse source of high purity biochemicals with a particular focus on product quality, availability, and customer support.

 

LKT Labs产品范围:

Cancer Biology

Cardiovascular

Endocrine Signaling and Immunology

Metabolic and GI Pathology

Microbiology

Natural Products

Neuroscience

Peptides

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艾美捷科技代理NeXtal Biotechnologies品牌。

NeXtal Biotechnologies 是一家专注于为结构生物学和药物发现领域提供高质量试剂、耗材和工具的公司。公司致力于支持科学家在蛋白质晶体学、小分子晶体学和药物筛选等领域的研究,提供从蛋白质纯化到晶体生长的全流程解决方案。NeXtal Biotechnologies核心业务领域:

(1)蛋白质纯化工具:NeXtal Biotechnologies 提供用于蛋白质纯化的工具和试剂,如亲和层析柱、蛋白质浓缩器和透析设备。

(2)晶体生长试剂:公司提供多种用于蛋白质和小分子晶体生长的试剂,包括结晶筛选试剂盒、缓冲液、沉淀剂和添加剂。

(3)结晶筛选试剂盒:NeXtal Biotechnologies 提供多种结晶筛选试剂盒,如 JCSG+、Morpheus 和 PACT,适用于不同类型的晶体生长实验。

(4)晶体学耗材:提供用于晶体学研究的耗材,如结晶板、密封膜、样品支架和低温冷冻工具。这些耗材与主流X射线衍射仪兼容,支持从晶体生长到数据收集的全流程。

(5)自动化晶体成像系统:NeXtal Biotechnologies 提供自动化晶体成像系统(如 Rock Imager),用于实时监测晶体生长过程,帮助科学家优化晶体生长条件。

(6)药物筛选工具:公司提供用于药物筛选的工具和试剂,如蛋白质-配体结合分析试剂盒和高通量筛选板。



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